PNCK | Calcium/calmodulin-dependent protein kinase type 1B
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Kinase Substrate Both Localization legend

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer
Gene
PNCK
Synonyms
-
Protein Name
Calcium/calmodulin-dependent protein kinase type 1B
UniProt ID
Q6P2M8 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000340586
NCBI Gene ID
139728
Molecular Weight
38500
Protein Length
343
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
2.7.11.17; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
Localization
Cytoplasm,Nucleus;
Function
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1 (By similarity).
Gene Ontology
GO:0005737; GO:0005634; GO:0005524; GO:0005516; GO:0004683