NOS3 | Nitric oxide synthase
 
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Sequence Viewer
Gene
NOS3
Synonyms
-
Protein Name
Nitric oxide synthase
UniProt ID
A0A090N8H8 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
-
NCBI Gene ID
Molecular Weight
133289
Protein Length
1203
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
1.14.13.39; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
H(+) + 2 L-arginine + 3 NADPH + 4 O2 = 4 H2O + 2 L-citrulline + 3 NADP(+) + 2 nitric oxide
Localization
Function
Produces nitric oxide (NO).
Gene Ontology
GO:0005516; GO:0050660; GO:0010181; GO:0020037; GO:0046872; GO:0050661; GO:0004517; GO:0006809