CaMKinet | Result

Gene

SLN

Synonyms

Protein Name

Sarcolipin

UniProt ID

O00631 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000304707

NCBI Gene ID

6588

Molecular Weight

3762

Protein Length

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 1jdm)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Sarcoplasmic reticulum membrane,Endoplasmic reticulum membrane;

Function

Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis (By similarity).

Gene Ontology

GO:0016021; GO:0016529; GO:0033017; GO:0051117; GO:0004857; GO:0006816; GO:1901877; GO:0090281; GO:1901020; GO:0043086; GO:0043242; GO:0120162; GO:1901881; GO:0051924; GO:1901894; GO:1901077; GO:0070296