Protein Name
Heat shock protein beta-6
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
17136
Protein Length
160
Protein Domain
3D Structure
(PDB ID : 4jus)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cytoplasm,Nucleus,Secreted;
Function
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.
Gene Ontology
GO:0005737; GO:0005576; GO:0005634; GO:0051087; GO:0042803; GO:0005212; GO:0051082; GO:0061077; GO:0010667; GO:0045766; GO:0006937