MYL12B | Myosin regulatory light chain 12B
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
MYL12B
Synonyms
MRLC2 MYLC2B
Protein Name
Myosin regulatory light chain 12B
UniProt ID
O14950 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000237500
NCBI Gene ID
10391010627
Molecular Weight
19779
Protein Length
172
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.
Gene Ontology
GO:0099738; GO:0005829; GO:0070062; GO:0016459; GO:0005509; GO:0006936