ERC2 | ERC protein 2
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
ERC2
Synonyms
KIAA0378
Protein Name
ERC protein 2
UniProt ID
O15083 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000288221
NCBI Gene ID
26059
Molecular Weight
110558
Protein Length
957
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Cell junction,Synapse,Cell junction,Synapse,Synaptosome,Cytoplasm,Cytoskeleton;
Function
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Gene Ontology
GO:0030054; GO:0005856; GO:0098982; GO:0098978; GO:0030426; GO:0048786; GO:0098831; GO:0042734; GO:0098882; GO:0016082