Protein Name
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
112966
Protein Length
1053
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Nucleus,Nucleoplasm;
Function
Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.
Gene Ontology
GO:0005829; GO:0000139; GO:0005654; GO:0048208