FANCA | Fanconi anemia group A protein
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
FANCA
Synonyms
FAA FACA FANCH
Protein Name
Fanconi anemia group A protein
UniProt ID
O15360 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000373952
NCBI Gene ID
2175
Molecular Weight
162775
Protein Length
1455
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus,Cytoplasm;
Function
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Gene Ontology
GO:0005737; GO:0043240; GO:0005654; GO:0005634; GO:0006281; GO:0008585; GO:0036297; GO:0008584; GO:0007140; GO:0065003; GO:2000348; GO:0042127; GO:0051090; GO:0050727; GO:0045589