PRPF3 | U4/U6 small nuclear ribonucleoprotein Prp3
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
PRPF3
Synonyms
HPRP3 PRP3
Protein Name
U4/U6 small nuclear ribonucleoprotein Prp3
UniProt ID
O43395 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000315379
NCBI Gene ID
9129
Molecular Weight
77529
Protein Length
683
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1x4q)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus,Nucleus speckle;
Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
Gene Ontology
GO:0015030; GO:0005829; GO:0016607; GO:0005654; GO:0005634; GO:0005681; GO:0071005; GO:0046540; GO:0042802; GO:0003723; GO:0006397; GO:0000398; GO:0008380; GO:0000375; GO:0000244