CaMKinet | Result

Gene

PLRG1

Synonyms

Protein Name

Pleiotropic regulator 1

UniProt ID

O43660 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000303191

NCBI Gene ID

5356

Molecular Weight

57194

Protein Length

514

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 4yvd)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Nucleus,Nucleus speckle;

Function

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:28076346). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing (PubMed:11101529, PubMed:11544257).

Gene Ontology

GO:0071013; GO:0080008; GO:0001650; GO:0031965; GO:0016607; GO:0005654; GO:0005634; GO:0000974; GO:0071007; GO:0000398; GO:1900087; GO:0034504