ADCY3 | Adenylate cyclase type 3
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
Synonyms
KIAA0511
Protein Name
Adenylate cyclase type 3
UniProt ID
O60266 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
128960
Protein Length
1144
Protein Domain
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
4.6.1.1; (BRENDA)
Catalytic Site
Catalytic Activity
ATP = 3',5'-cyclic AMP + diphosphate
Localization
Cell membrane,Cytoplasm,Cell projection,Cilium,Golgi apparatus;
Function
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet.
Gene Ontology
GO:0005929; GO:0005737; GO:0005794; GO:0016021; GO:0005887; GO:0016020; GO:0005886; GO:0004016; GO:0005524; GO:0005516; GO:0046872; GO:0007340; GO:0007189; GO:0007193; GO:0006171; GO:1904322; GO:0071377; GO:0030317; GO:0007186; GO:0008355; GO:0003091; GO:0007608; GO:0007165; GO:0007338
 
Gene Ontology