TBC1D4 | TBC1 domain family member 4
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
TBC1D4
Synonyms
AS160 KIAA0603
Protein Name
TBC1 domain family member 4
UniProt ID
O60343 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000366852
NCBI Gene ID
9882
Molecular Weight
146563
Protein Length
1298
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 3qyb)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm;
Function
May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.
Gene Ontology
GO:0005829; GO:0031982; GO:0005096; GO:0017137; GO:0090630; GO:0032869; GO:0006886; GO:0031339; GO:0016192