HBP1 | HMG box-containing protein 1
 
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Sequence Viewer
Gene
HBP1
Synonyms
-
Protein Name
HMG box-containing protein 1
UniProt ID
O60381 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000222574
NCBI Gene ID
26959
Molecular Weight
57645
Protein Length
514
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2e6o)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus;
Function
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
Gene Ontology
GO:0016607; GO:0005654; GO:0003677; GO:0000981; GO:0003723; GO:0007050; GO:0016055