STK17B | Serine/threonine-protein kinase 17B
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer
Gene
Synonyms
DRAK2
Protein Name
Serine/threonine-protein kinase 17B
UniProt ID
O94768 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
42344
Protein Length
372
Protein Domain
3D Structure
(PDB ID : 3lm0)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
2.7.11.1; (BRENDA)
Catalytic Site
Catalytic Activity
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
Localization
Nucleus,Cell membrane,Endoplasmic reticulum-Golgi intermediate compartment;
Function
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
Gene Ontology
GO:0015629; GO:0005793; GO:0005634; GO:0005886; GO:0005524; GO:0004672; GO:0004674; GO:0006915; GO:0035556; GO:2000271; GO:0046777; GO:0006468
 
Gene Ontology