KIF4A | Chromosome-associated kinesin KIF4A
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
KIF4A
Synonyms
KIF4
Protein Name
Chromosome-associated kinesin KIF4A
UniProt ID
O95239 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000363524
NCBI Gene ID
24137
Molecular Weight
139881
Protein Length
1232
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus matrix,Cytoplasm,Cytoskeleton,Spindle,Midbody,Chromosome;
Function
Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
Gene Ontology
GO:1904115; GO:0005694; GO:0005737; GO:0005829; GO:0045171; GO:0005871; GO:0016020; GO:0005874; GO:0030496; GO:0016363; GO:0005654; GO:0005876; GO:0005524; GO:0016887; GO:0003677; GO:0008017; GO:0003777; GO:0008089; GO:0019886; GO:0007018; GO:0000281; GO:0051256; GO:0007052; GO:0006996; GO:0006890
 
Gene Ontology