BAG2 | BAG family molecular chaperone regulator 2
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
BAG2
Synonyms
-
Protein Name
BAG family molecular chaperone regulator 2
UniProt ID
O95816 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000359727
NCBI Gene ID
9532
Molecular Weight
23772
Protein Length
211
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release (PubMed:24318877, PubMed:9873016).
Gene Ontology
GO:0030424; GO:0101031; GO:0005829; GO:0030425; GO:1901588; GO:0000774; GO:0051087; GO:0031072; GO:0042802; GO:0044325; GO:0048156; GO:0031625; GO:0032091; GO:0031397; GO:1904667; GO:1901800; GO:0010954; GO:0006457; GO:0019538; GO:0050821; GO:1900034
 
Gene Ontology