PYGM | Glycogen phosphorylase, muscle form
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
PYGM
Synonyms
-
Protein Name
Glycogen phosphorylase, muscle form
UniProt ID
P00489 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
-
NCBI Gene ID
100008972
Molecular Weight
97289
Protein Length
843
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1a8i)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
2.4.1.1; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate
Localization
Function
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Gene Ontology
GO:0098723; GO:0008184; GO:0102250; GO:0000166; GO:0030170; GO:0102499; GO:0005977