CRYAB | Alpha-crystallin B chain
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
CRYAB
Synonyms
CRYA2 HSPB5
Protein Name
Alpha-crystallin B chain
UniProt ID
P02511 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000227251
NCBI Gene ID
1410
Molecular Weight
20159
Protein Length
175
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2klr)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Nucleus;
Function
May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
Gene Ontology
GO:0032432; GO:0030424; GO:0097512; GO:0009986; GO:0005737; GO:0005829; GO:0043197; GO:0070062; GO:0005794; GO:0031430; GO:0015630; GO:0005739; GO:0005654; GO:0005634; GO:0043204; GO:0014069; GO:0097060; GO:0030018; GO:0001540; GO:0042802; GO:0046872; GO:0008017; GO:0042803; GO:0044877; GO:0005212; GO:0051082; GO:0060561; GO:0071480; GO:0002088; GO:0031109; GO:0010259; GO:0006936; GO:0007517; GO:1905907; GO:0043066; GO:0030308; GO:0043154; GO:0010629; GO:0032387; GO:0032463; GO:2000378; GO:0006457; GO:0051260; GO:0050821; GO:0010941; GO:1900034; GO:0032355; GO:0042542; GO:0001666; GO:0051403; GO:0007021
 
Gene Ontology