NEFL | Neurofilament light polypeptide
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
NEFL
Synonyms
NF68 NFL
Protein Name
Neurofilament light polypeptide
UniProt ID
P07196 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000482169
NCBI Gene ID
4747
Molecular Weight
61517
Protein Length
543
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
Gene Ontology
GO:0030424; GO:1904115; GO:0098981; GO:0005737; GO:0005829; GO:0030426; GO:0005883; GO:0031594; GO:0099160; GO:0099182; GO:0098685; GO:0042802; GO:0043274; GO:0030674; GO:0008022; GO:0019904; GO:0046982; GO:0005088; GO:0005200; GO:0099184; GO:0008089; GO:0019896; GO:0021987; GO:0021766; GO:0045109; GO:0045105; GO:0040011; GO:0000165; GO:0000226; GO:0043524; GO:0033693; GO:0060052; GO:0050885; GO:0048812; GO:0014012; GO:0050772; GO:0051258; GO:0031133; GO:1903937; GO:0051412; GO:0043434; GO:1903935; GO:0008090; GO:0021510; GO:0060074
 
Gene Ontology