CaMKinet | Result

Gene

ADRB2

Synonyms

ADRB2R B2AR

Protein Name

Beta-2 adrenergic receptor

UniProt ID

P07550 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000305372

NCBI Gene ID

154

Molecular Weight

46459

Protein Length

413

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 1gq4)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cell membrane,Early endosome;

Function

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gene Ontology

GO:0016324; GO:0030665; GO:0005769; GO:0005768; GO:0010008; GO:0005887; GO:0005764; GO:0016020; GO:0005634; GO:0005886; GO:0043235; GO:0008179; GO:0004935; GO:0001540; GO:0004941; GO:0051379; GO:0051380; GO:0015459; GO:0042803; GO:0044877; GO:0007190; GO:0007171; GO:0071880; GO:0007188; GO:0071875; GO:0045453; GO:0050873; GO:0007166; GO:1904646; GO:0002032; GO:0002024; GO:0008333; GO:0007186; GO:0031649; GO:0061024; GO:0040015; GO:0045986; GO:0002025; GO:2000969; GO:1901098; GO:0030501; GO:2000481; GO:0120162; GO:1904504; GO:0043410; GO:0061885; GO:0010739; GO:0071902; GO:0031398; GO:0045944; GO:0016579; GO:0006898; GO:0002028; GO:0009409; GO:1990911