CaMKinet | Result

Gene

Synonyms

Protein Name

Fumarate hydratase, mitochondrial

UniProt ID

P07954 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000355518

NCBI Gene ID

Molecular Weight

54637

Protein Length

510

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 3e04)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

4.2.1.2; (BRENDA)

Catalytic Site

Catalytic Activity

(S)-malate = fumarate + H2O

Localization

Isoform Mitochondrial: Mitochondrion;Isoform Cytoplasmic: Cytoplasm;

Function

Also acts as a tumor suppressor.

Gene Ontology

GO:0005737; GO:0070062; GO:0005759; GO:0005739; GO:0045239; GO:0004333; GO:0006106; GO:0048873; GO:0006108; GO:0120162; GO:0006099