MPZ | Myelin protein P0
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
MPZ
Synonyms
-
Protein Name
Myelin protein P0
UniProt ID
P10522 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSBTAP00000045141
NCBI Gene ID
539462
Molecular Weight
27452
Protein Length
248
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cell membrane;
Function
Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
Gene Ontology
GO:0005887; GO:0043209; GO:0005886; GO:0098743; GO:0098742; GO:0042552