CaMKinet | Result

Gene

PYGB

Synonyms

Protein Name

Glycogen phosphorylase, brain form

UniProt ID

P11216 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000216962

NCBI Gene ID

5834

Molecular Weight

96696

Protein Length

843

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 5iko)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

2.4.1.1; (BRENDA)

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate

Localization

Function

Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852). Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228). Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228). However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).

Gene Ontology

GO:0035578; GO:0005737; GO:0070062; GO:0005576; GO:0016020; GO:0008184; GO:0102250; GO:0030170; GO:0102499; GO:0005980; GO:0043312