PRPS2 | Ribose-phosphate pyrophosphokinase 2
 
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Sequence Viewer
Gene
PRPS2
Synonyms
-
Protein Name
Ribose-phosphate pyrophosphokinase 2
UniProt ID
P11908 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000370043
NCBI Gene ID
5634
Molecular Weight
34769
Protein Length
318
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
2.7.6.1; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)
Localization
Function
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
Gene Ontology
GO:0005737; GO:0002189; GO:0043531; GO:0016208; GO:0005524; GO:0030246; GO:0019003; GO:0042802; GO:0016301; GO:0000287; GO:0042803; GO:0004749; GO:0006015; GO:0006167; GO:0031100; GO:0006139; GO:0009116; GO:0009165; GO:0006164