Hspb1 | Heat shock protein beta-1
 
Sequence Viewer
Gene
Hspb1
Synonyms
Hsp25 Hsp27
Protein Name
Heat shock protein beta-1
UniProt ID
P14602 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSMUSP00000005077
NCBI Gene ID
15507
Molecular Weight
23014
Protein Length
209
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Nucleus,Cytoplasm,Cytoskeleton,Spindle;
Function
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization (PubMed:17661394). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (By similarity).
Gene Ontology
GO:0030424; GO:1904115; GO:0097512; GO:0043292; GO:0005737; GO:0030425; GO:0031674; GO:0031430; GO:0005634; GO:0043204; GO:0005886; GO:0098839; GO:0000502; GO:0005819; GO:0045202; GO:0030018; GO:0042802; GO:0044183; GO:0042803; GO:0019901; GO:0005080; GO:0008426; GO:0043130; GO:0099641; GO:0035924; GO:0061077; GO:0035556; GO:2001234; GO:1903202; GO:1902176; GO:0006469; GO:0045766; GO:0043536; GO:2001028; GO:0038033; GO:0032731; GO:0010976; GO:0042535; GO:0043122; GO:0001932; GO:0006986; GO:0009615
 
Gene Ontology