CaMKinet | Result

Gene

ETS1

Synonyms

EWSR2

Protein Name

Protein C-ets-1

UniProt ID

P14921 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000324578

NCBI Gene ID

2113

Molecular Weight

50408

Protein Length

441

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 1gvj)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cytoplasm,Nucleus;

Function

Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.

Gene Ontology

GO:0005737; GO:0005654; GO:0005634; GO:0005667; GO:0003677; GO:0001228; GO:0003700; GO:0000981; GO:0035035; GO:0042802; GO:0000978; GO:0008134; GO:0060055; GO:0030154; GO:0048870; GO:0070301; GO:0044849; GO:0007565; GO:0021854; GO:0006955; GO:0045786; GO:0008285; GO:0050728; GO:0021983; GO:0030578; GO:0045766; GO:0043536; GO:0008284; GO:0051272; GO:0010595; GO:0045648; GO:0010628; GO:0050729; GO:1904996; GO:0045944; GO:0045893; GO:0061614; GO:0045765; GO:0042981; GO:0010715; GO:0006357; GO:0046677; GO:0032355; GO:0001666; GO:0070555; GO:0034616; GO:0009612; GO:0006366