CaMKinet | Result

Gene

STMN1

Synonyms

C1orf215 LAP18 OP18

Protein Name

Stathmin

UniProt ID

P16949 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000350531

NCBI Gene ID

3925

Molecular Weight

17303

Protein Length

149

Protein Domain

InterPro | Pfam

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cytoplasm,Cytoskeleton;

Function

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity).

Gene Ontology

GO:0005737; GO:0005829; GO:0070062; GO:0005622; GO:0016020; GO:0005874; GO:0043005; GO:0015631; GO:0007409; GO:0007420; GO:0061436; GO:0048012; GO:0035556; GO:0007019; GO:0000281; GO:0007052; GO:1905098; GO:0031115; GO:0035024; GO:0051497; GO:0070495; GO:0031175; GO:0051272; GO:0051493; GO:0031110; GO:0009615; GO:0007165