XRCC1 | DNA repair protein XRCC1
 
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Sequence Viewer
Gene
XRCC1
Synonyms
-
Protein Name
DNA repair protein XRCC1
UniProt ID
P18887 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000262887
NCBI Gene ID
7515
Molecular Weight
69477
Protein Length
633
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1cdz)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus;
Function
Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Probably during DNA repair, negatively regulates ADP-ribose levels by modulating ADP-ribosyltransferase PARP1 activity.
Gene Ontology
GO:0070522; GO:0000790; GO:0000784; GO:0005730; GO:0005654; GO:0005634; GO:1990599; GO:0003909; GO:0019899; GO:0032356; GO:0006284; GO:0006288; GO:0021587; GO:0000724; GO:0006303; GO:0021766; GO:1905765; GO:0010836; GO:0006297; GO:1904877; GO:1903518; GO:1990414; GO:0042493; GO:0033194; GO:0001666; GO:0010033; GO:0000012; GO:0061819; GO:0006283; GO:0050882
 
Gene Ontology