ELK1 | ETS domain-containing protein Elk-1
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer
Gene
ELK1
Synonyms
-
Protein Name
ETS domain-containing protein Elk-1
UniProt ID
P19419 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000247161
NCBI Gene ID
2002
Molecular Weight
44888
Protein Length
428
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1dux)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus;
Function
Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity).
Gene Ontology
GO:0043679; GO:0030425; GO:0005739; GO:0043025; GO:0005654; GO:0005634; GO:0003682; GO:0001228; GO:0003700; GO:0000981; GO:0000978; GO:0001085; GO:0030154; GO:0071480; GO:0071394; GO:1901216; GO:0045944; GO:0045893; GO:0006357; GO:0071774; GO:0009416
 
Gene Ontology