Gabrg2 | Gamma-aminobutyric acid receptor subunit gamma-2
 
Sequence Viewer
Gene
Gabrg2
Synonyms
-
Protein Name
Gamma-aminobutyric acid receptor subunit gamma-2
UniProt ID
P22723 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSMUSP00000064739
NCBI Gene ID
14406
Molecular Weight
55099
Protein Length
474
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cell junction,Synapse,Postsynaptic cell membrane,Cell membrane,Cell projection,Dendrite,Cytoplasmic vesicle membrane;
Function
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
Gene Ontology
GO:0030424; GO:0030054; GO:0034707; GO:0005737; GO:0030659; GO:0032590; GO:1902710; GO:1902711; GO:0098982; GO:0098978; GO:0060077; GO:0005887; GO:0099060; GO:0043005; GO:0098794; GO:0045202; GO:0005254; GO:0004890; GO:0022851; GO:0005237; GO:1904315; GO:0030534; GO:0071420; GO:0007268; GO:1902476; GO:0007214; GO:0034220; GO:0050877; GO:0009791; GO:0042391; GO:0060078; GO:0007165; GO:0051932
 
Gene Ontology