EIF4B | Eukaryotic translation initiation factor 4B
 
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Sequence Viewer
Gene
EIF4B
Synonyms
-
Protein Name
Eukaryotic translation initiation factor 4B
UniProt ID
P23588 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000262056
NCBI Gene ID
1975
Molecular Weight
69151
Protein Length
611
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1wi8)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Gene Ontology
GO:0005829; GO:0016281; GO:0005844; GO:0043024; GO:0003723; GO:0033592; GO:0034057; GO:0003743; GO:0002181; GO:0097010; GO:0001731; GO:0006446; GO:0006413
 
Gene Ontology