PTPN3 | Tyrosine-protein phosphatase non-receptor type 3
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
PTPN3
Synonyms
PTPH1
Protein Name
Tyrosine-protein phosphatase non-receptor type 3
UniProt ID
P26045 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000363667
NCBI Gene ID
5774
Molecular Weight
103990
Protein Length
913
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2b49)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
3.1.3.48; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate
Localization
Cell membrane,Cytoplasm,Cytoskeleton;
Function
May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.
Gene Ontology
GO:0005737; GO:0009898; GO:0005856; GO:0005886; GO:0051117; GO:0008092; GO:0001784; GO:0004725; GO:0017080; GO:0097421; GO:0042059; GO:0051045; GO:0045930; GO:0006470; GO:0098902; GO:2000649
 
Gene Ontology