Braf | Serine/threonine-protein kinase B-raf
 
Sequence Viewer
Gene
Braf
Synonyms
B-raf
Protein Name
Serine/threonine-protein kinase B-raf
UniProt ID
P28028 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSMUSP00000002487
NCBI Gene ID
109880
Molecular Weight
88780
Protein Length
804
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
2.7.11.1; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
Localization
Nucleus,Cytoplasm,Cell membrane;
Function
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron (By similarity).
Gene Ontology
GO:0044297; GO:0005737; GO:0005829; GO:0043231; GO:0016020; GO:0005739; GO:0043005; GO:0005634; GO:0005886; GO:0005524; GO:0005509; GO:0042802; GO:0004709; GO:0031434; GO:0046982; GO:0004672; GO:0004674; GO:0017016; GO:0046632; GO:0043369; GO:0043367; GO:0030154; GO:0071277; GO:0035690; GO:1990090; GO:0090150; GO:0060324; GO:0060323; GO:0060291; GO:0000165; GO:0002318; GO:0043066; GO:2000352; GO:0010764; GO:0043524; GO:2000301; GO:0048680; GO:0050772; GO:0070374; GO:0010628; GO:0010828; GO:0033138; GO:0051496; GO:1900026; GO:0043368; GO:0051291; GO:0006468; GO:0048679; GO:0042127; GO:0045580; GO:0051591; GO:0043434; GO:0035019; GO:0050852; GO:0048538; GO:0030878; GO:0070413; GO:0008542
 
Gene Ontology