Kif3a | Kinesin-like protein KIF3A
 
Sequence Viewer
Gene
Kif3a
Synonyms
Kif3
Protein Name
Kinesin-like protein KIF3A
UniProt ID
P28741 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSMUSP00000112782
NCBI Gene ID
16568
Molecular Weight
80170
Protein Length
701
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 5jvr)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Cytoskeleton,Cell projection,Cilium,Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Centriole;
Function
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation (PubMed:21670265). Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitement of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole (PubMed:23386061).
Gene Ontology
GO:1904115; GO:0005930; GO:0005814; GO:0005813; GO:0005929; GO:0005829; GO:0005871; GO:0016939; GO:0005874; GO:0015630; GO:0031514; GO:0043005; GO:0043025; GO:0032391; GO:0097470; GO:0005524; GO:0016887; GO:0120170; GO:0019894; GO:0008017; GO:0003777; GO:0019903; GO:0044877; GO:0017137; GO:0030507; GO:0009952; GO:0008089; GO:0007411; GO:0010457; GO:0060271; GO:0021542; GO:0007368; GO:0021904; GO:0009953; GO:0036334; GO:0008544; GO:0007507; GO:0001947; GO:0001701; GO:0060122; GO:0001822; GO:0034454; GO:0007018; GO:0044458; GO:0061351; GO:0021915; GO:1905515; GO:1905128; GO:0050679; GO:2000771; GO:0090316; GO:0048260; GO:1902414; GO:0015031; GO:0007224
 
Gene Ontology