Itpr2 | Inositol 1,4,5-trisphosphate receptor type 2
 
Sequence Viewer
Gene
Itpr2
Synonyms
-
Protein Name
Inositol 1,4,5-trisphosphate receptor type 2
UniProt ID
P29995 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
-
NCBI Gene ID
81678
Molecular Weight
307058
Protein Length
2701
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Endoplasmic reticulum membrane;
Function
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity).
Gene Ontology
GO:0030424; GO:0005737; GO:0030659; GO:0005783; GO:0005789; GO:0016021; GO:0043209; GO:0005886; GO:0016529; GO:0030667; GO:0005509; GO:0070679; GO:0005220; GO:0035091; GO:0071456; GO:0051209