CaMKinet | Result

Gene

PKLR

Synonyms

PK1 PKL

Protein Name

Pyruvate kinase PKLR

UniProt ID

P30613 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000339933

NCBI Gene ID

5313

Molecular Weight

61830

Protein Length

574

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 2vgb)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

2.7.1.40; (BRENDA)

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate

Localization

Function

Plays a key role in glycolysis.

Gene Ontology

GO:0005737; GO:0005829; GO:0070062; GO:0005524; GO:0016301; GO:0000287; GO:0030955; GO:0004743; GO:0061621; GO:0071872; GO:0032869; GO:0006096; GO:0033198; GO:0051591; GO:0009749; GO:0009408; GO:0001666; GO:0010226