CaMKinet | Result

Gene

MC4R

Synonyms

Protein Name

Melanocortin receptor 4

UniProt ID

P32245 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000299766

NCBI Gene ID

4160

Molecular Weight

36943

Protein Length

332

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 2iqp)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cell membrane;

Function

Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

Gene Ontology

GO:0016021; GO:0005634; GO:0005886; GO:0004977; GO:0004980; GO:0042923; GO:0017046; GO:0031625; GO:0007189; GO:0007188; GO:0002024; GO:0006112; GO:0007631; GO:0007186; GO:0030073; GO:2000252; GO:0045780; GO:2000821; GO:0019222; GO:0032868