Protein Name
Syntaxin-1A
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
33067
Protein Length
288
Protein Domain
3D Structure
(PDB ID : 1br0)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cytoplasmic vesicle,Secretory vesicle,Synaptic vesicle membrane,Cell membrane,Cell junction,Synapse,Synaptosome;
Function
Plays a role in hormone and neurotransmitter exocytosis (PubMed:17301173, PubMed:18167541, PubMed:20484665, PubMed:22411134, PubMed:7901002). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Gene Ontology
GO:0042641; GO:0030424; GO:0030054; GO:0012505; GO:0098978; GO:0016021; GO:0099056; GO:0030285; GO:0043229; GO:0031965; GO:0005886; GO:0014069; GO:0048787; GO:0042734; GO:0032991; GO:0030141; GO:0031201; GO:0008021; GO:0030672; GO:0070044; GO:0070032; GO:0070033; GO:0043008; GO:0019855; GO:0048306; GO:0019869; GO:0044325; GO:0019900; GO:0017022; GO:0032028; GO:0030674; GO:0019904; GO:0046982; GO:0047485; GO:0005484; GO:0000149; GO:0006887; GO:0006886; GO:0098815; GO:0006836; GO:0045956; GO:0033605; GO:2000463; GO:0045921; GO:0001956; GO:0010701; GO:0072657; GO:0017157; GO:0010807; GO:0009629; GO:0035493; GO:0016081; GO:0016079; GO:0031629; GO:0048278; GO:0006906