HIST1H2BB | Histone H2B type 1-B
 
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Sequence Viewer
Gene
HIST1H2BB
Synonyms
H2BFF
Protein Name
Histone H2B type 1-B
UniProt ID
P33778 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000482674
NCBI Gene ID
3018
Molecular Weight
13950
Protein Length
126
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 3x1s)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus,Chromosome;
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene Ontology
GO:0005829; GO:0000784; GO:0005654; GO:0000786; GO:0005634; GO:0003677; GO:0046982; GO:0006334; GO:0016567