CaMKinet | Result

Gene

HRH1

Synonyms

Protein Name

Histamine H1 receptor

UniProt ID

P35367 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000380247

NCBI Gene ID

3269

Molecular Weight

55784

Protein Length

487

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 3rze)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cell membrane;

Function

In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.

Gene Ontology

GO:0005829; GO:0030425; GO:0005887; GO:0005886; GO:0004930; GO:0004993; GO:0004969; GO:0030594; GO:0071420; GO:0007268; GO:0048245; GO:0007186; GO:0007187; GO:0006954; GO:0048016; GO:0007613; GO:0007200; GO:0032962; GO:0045907; GO:0048167; GO:0043114; GO:0008542