CaMKinet | Result

Gene

HNF4A

Synonyms

HNF4 NR2A1 TCF14

Protein Name

Hepatocyte nuclear factor 4-alpha

UniProt ID

P41235 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000312987

NCBI Gene ID

3172

Molecular Weight

52785

Protein Length

474

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 1pzl)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Nucleus;

Function

Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine.

Gene Ontology

GO:0005737; GO:0005654; GO:0005634; GO:0003677; GO:0001228; GO:0003700; GO:0000981; GO:0005504; GO:0004879; GO:0042803; GO:0001102; GO:0000978; GO:0005102; GO:0003707; GO:0044212; GO:0008270; GO:0007596; GO:0042632; GO:0042593; GO:0070365; GO:0055088; GO:0006629; GO:0030308; GO:0008285; GO:0006591; GO:0055091; GO:0045944; GO:0045893; GO:0010470; GO:0060398; GO:0050796; GO:0019216; GO:0006357; GO:0009749; GO:0007548; GO:0023019; GO:0060395; GO:0006367; GO:0070328; GO:0003323; GO:0006805