Localization
Cell membrane,Endoplasmic reticulum membrane,Cell junction,Synapse,Postsynaptic cell membrane,Cell junction,Synapse,Postsynaptic cell membrane,Postsynaptic density,Cell projection,Dendrite,Cell projection,Dendritic spine,Early endosome membrane,Recycling endosome membrane;
Function
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Gene Ontology
GO:0032281; GO:0044308; GO:0030054; GO:0009986; GO:0030425; GO:0043197; GO:0032591; GO:0031901; GO:0030666; GO:0005789; GO:0033116; GO:0012507; GO:0098978; GO:0000139; GO:0099061; GO:0044309; GO:0043025; GO:0005886; GO:0014069; GO:0055037; GO:0055038; GO:0097060; GO:0008021; GO:0004971; GO:0001540; GO:0008066; GO:0099583; GO:0030165; GO:1904315; GO:0007268; GO:0048208; GO:0006888; GO:0007616; GO:0060292; GO:0031623; GO:0007165