CaMKinet | Result

Gene

VIM

Synonyms

Protein Name

Vimentin

UniProt ID

P48616 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSBTAP00000024572

NCBI Gene ID

280955

Molecular Weight

53728

Protein Length

466

Protein Domain

InterPro | Pfam

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cytoplasm,Cytoplasm,Cytoskeleton,Nucleus matrix;

Function

Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.

Gene Ontology

GO:0031252; GO:0005737; GO:0005829; GO:0005882; GO:0043005; GO:0016363; GO:0005634; GO:0005777; GO:0045335; GO:0005886; GO:0005844; GO:0003725; GO:0042802; GO:1990254; GO:0008022; GO:0019904; GO:0097110; GO:0005200; GO:0005212; GO:0014002; GO:0060020; GO:0071346; GO:0071222; GO:0071225; GO:0001701; GO:0045109; GO:0070307; GO:0010977; GO:0032967; GO:0045727; GO:0043488; GO:0060395