HNRNPM | Heterogeneous nuclear ribonucleoprotein M
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
HNRNPM
Synonyms
HNRPM NAGR1
Protein Name
Heterogeneous nuclear ribonucleoprotein M
UniProt ID
P52272 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000325376
NCBI Gene ID
4670
Molecular Weight
77516
Protein Length
730
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2dgv)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus,Nucleolus;
Function
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
Gene Ontology
GO:0071013; GO:0062023; GO:0005737; GO:0070062; GO:0016020; GO:0016363; GO:0005730; GO:0005654; GO:0005634; GO:0042382; GO:0071014; GO:1990904; GO:0005681; GO:0003729; GO:0019904; GO:0003723; GO:0000380; GO:0008543; GO:0000398; GO:2000815; GO:0016070
 
Gene Ontology