CaMKinet | Result

Gene

Synonyms

Protein Name

cAMP-specific 3',5'-cyclic phosphodiesterase 4A

UniProt ID

P54748 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

NCBI Gene ID

Molecular Weight

93439

Protein Length

844

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 1loi)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

3.1.4.53; (BRENDA)

Catalytic Site

Catalytic Activity

3',5'-cyclic AMP + H2O = AMP + H(+)

Localization

Cytoplasm,Perinuclear region;

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Gene Ontology

GO:0005737; GO:0005829; GO:0005634; GO:0048471; GO:0098685; GO:0004115; GO:0030552; GO:0046872; GO:0006198; GO:0050804; GO:0042493; GO:0007165