RRAD | GTP-binding protein RAD
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer
Gene
RRAD
Synonyms
RAD
Protein Name
GTP-binding protein RAD
UniProt ID
P55042 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000299759
NCBI Gene ID
6236
Molecular Weight
33245
Protein Length
308
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2dpx)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cell membrane;
Function
May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
Gene Ontology
GO:0005886; GO:0005246; GO:0005516; GO:0005525; GO:0003924; GO:1901842; GO:0007264