YWHAZ | 14-3-3 protein zeta/delta
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
YWHAZ
Synonyms
-
Protein Name
14-3-3 protein zeta/delta
UniProt ID
P63104 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000309503
NCBI Gene ID
7534
Molecular Weight
27745
Protein Length
245
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1ib1)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Melanosome;
Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Gene Ontology
GO:0072562; GO:0005737; GO:0005829; GO:0070062; GO:0005615; GO:0005925; GO:0098978; GO:0042470; GO:0005739; GO:0005654; GO:0005634; GO:0031982; GO:0045296; GO:0042802; GO:0044325; GO:0019904; GO:0019901; GO:0003723; GO:0008134; GO:0031625; GO:0019221; GO:0051683; GO:0090168; GO:0061024; GO:0043066; GO:0030168; GO:1900740; GO:0043488; GO:0090128; GO:0007165
 
Gene Ontology