Evl | Ena/VASP-like protein
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
Evl
Synonyms
-
Protein Name
Ena/VASP-like protein
UniProt ID
P70429 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSMUSP00000021689
NCBI Gene ID
14026
Molecular Weight
44337
Protein Length
414
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1qc6)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Cytoskeleton,Cytoplasm,Cytoskeleton,Stress fiber,Cell projection,Lamellipodium;
Function
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization.
Gene Ontology
GO:0005737; GO:0005856; GO:0005925; GO:0030027; GO:0045335; GO:0003779; GO:0005522; GO:0017124; GO:0030048; GO:0045010; GO:0008154; GO:0007411; GO:0051016; GO:0071346; GO:0010633; GO:1900028; GO:0030168; GO:0030838; GO:0051496; GO:0051289
 
Gene Ontology