Protein Name
Scavenger receptor class B member 1
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
56957
Protein Length
509
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cell membrane,Membrane,Caveola;
Function
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.
Gene Ontology
GO:0005901; GO:0009986; GO:0005737; GO:0005887; GO:0043231; GO:0031528; GO:0005886; GO:0001540; GO:0034186; GO:0008035; GO:0070506; GO:0005319; GO:0001530; GO:0001875; GO:0030169; GO:0001786; GO:0042803; GO:0044406; GO:0006702; GO:0043534; GO:0006707; GO:0033344; GO:0042632; GO:0070508; GO:0032497; GO:0001935; GO:0034384; GO:0034375; GO:0050892; GO:0006869; GO:0015920; GO:0034383; GO:0006910; GO:0015914; GO:0010886; GO:0051000; GO:0010867; GO:0043654; GO:0050764; GO:0010899; GO:0043691; GO:0006694; GO:0070328; GO:0035461