SLC6A3 | Sodium-dependent dopamine transporter
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
SLC6A3
Synonyms
DAT1
Protein Name
Sodium-dependent dopamine transporter
UniProt ID
Q01959 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000270349
NCBI Gene ID
6531
Molecular Weight
68495
Protein Length
620
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cell membrane;
Function
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Gene Ontology
GO:0030424; GO:0009986; GO:0005737; GO:0098691; GO:0016600; GO:0016021; GO:0099055; GO:0099056; GO:0045121; GO:0043005; GO:0043025; GO:0005886; GO:0035240; GO:0005330; GO:0046872; GO:0008504; GO:0005328; GO:0002020; GO:0047485; GO:0051721; GO:0044877; GO:0005102; GO:0021984; GO:0007568; GO:0042416; GO:0042420; GO:0015872; GO:0090494; GO:0007595; GO:0007626; GO:0015844; GO:0042136; GO:0001504; GO:0040018; GO:0060134; GO:0042053; GO:0051591; GO:0042220; GO:0045471; GO:0010039; GO:0035094; GO:0007608
 
Gene Ontology